Use of Bordetella bronchiseptica and Bordetella pertussis as live vaccines and vectors for heterologous antigens.
نویسندگان
چکیده
Bordetella pertussis and Bordetella bronchiseptica are respiratory pathogens of humans and animals respectively. Unlike many bacteria, they are able to efficiently colonise healthy ciliated respiratory mucosa. This characteristic of Bordetella spp. can potentially be exploited to develop efficient live vaccines and vectors for delivery of heterologous antigens to the respiratory tract. Here we review the progress in this area.
منابع مشابه
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ورودعنوان ژورنال:
- FEMS immunology and medical microbiology
دوره 37 2-3 شماره
صفحات -
تاریخ انتشار 2003